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Can Vitamin C Build Muscle Strength ?

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Vitamin C, also known as ascorbic acid or L-ascorbate, is an essential vitamin to the human body. It could very well be one of the safest and most important vitamins you could take on a daily basis. Vitamin C is the most known as the first thing people go for whenever they have a cold. It is a water-soluble vitamin that is necessary for normal growth and development. Since it is water-soluble, extra amounts that the body doesn’t use leaves the body through urine within 24 hours.

It is an antioxidant as well. Antioxidants are nutrients that block some of the damage caused by free radicals, which are by-products that result when our transform food into energy. Antioxidants also possibly help reduce the damage to the body caused by toxic chemicals and pollutants such as cigarette smoke.

Why Vitamin C is required for Human Health ?

Vitamin C is required for the growth and repair of tissues in all parts of your body. It is used to form collagen, a protein used to make skin, scar tissue, tendons, ligaments, and blood vessels. It is also essentials for the healing of wounds, and for the repair and maintenance of people’s cartilage, bones, and teeth. C also helps with blood pressure by strengthening the walls of the arteries. It can also prevent damage to cells caused by aging as well as help reduce stress.

Everybody needs Vitamin C, whether you are a hard training athlete, or an everyday person that is just trying to get in shape. C can help protect the immune system and help bodybuilders recover from intense training.

It helps in protein metabolism. It not only provides our body with certain necessary proteins but also blocks the synthesis of vital proteins that cause infection and inflammation. It is also believed that vitamin C usage may support efforts to prevent heart disease, stroke, and cancer later in life.

Vitamins are substances that your body needs to grow and develop normally. Vitamins help your body grow and work the way it should There are 13 vitamins your body needs. They are: vitamins A, C, D, E, K, and the B vitamins (thiamine, riboflavin, niacin, pantothenic acid, biotin, B6, B12, and folate).Vitamins have different jobs—helping you resist infections, keeping your nerves healthy, and helping your body get energy from food or your blood to clot properly.
vitamins are substances that your body needs to grow and develop normally. Vitamin C is an antioxidant. It is important for your skin, bones, and connective tissue. It promotes healing and helps the body absorb iron.

Sources Of Vitamin C

Primary known sources include:

  • Cantaloupe.
  • Orange.
  • Broccoli.
  • Red cabbage.
  • Green pepper.
  • Red pepper.
  • Kiwi.
  • Tomatoes.
  • Strawberries.
  • Raspberries.
  • Pineapple.
  • Blueberries.
  • Cranberries.
  • Papaya.
  • Mango.
  • Watermelon.
  • Cauliflower.
  • Brussels sprouts.

How much C is too much depends on the person taking it. One thing you should not do is take it on an empty stomach. This can lead to indigestion. Also, do not take a lot at one time. Taking extra-large dosages of C at one time can cause diarrhea, disturbed sleep, and nausea. Do not take more than 1,000mg of Vitamin C at one time.

Vitamin C comes from fruits and vegetables. Good sources include citrus, red and green peppers, tomatoes, broccoli, and greens. Some juices and cereals have added vitamin C.

Some people may need extra vitamin C:

  • Pregnant/breastfeeding women.
  • Smokers.
  • People recovering from surgery.
  • Burn victims.

How Vitamin C useful for muscle strength?

New research shows that vitamin C could help over 50s retain muscle mass in later life. The study shows that older people who eat plenty of vitamin C — commonly found in citrus fruits, berries and vegetables — have the best skeletal muscle mass.
Vitamin C could be the key to better muscles in later life, according to new research from the University of East Anglia (UEA). A study published today shows that older people who eat plenty of vitamin C — commonly found in citrus fruits, berries, and vegetables — have the best skeletal muscle mass. This is important because people tend to lose skeletal muscle mass as they get older — leading to sarcopenia (a condition characterized by loss of skeletal muscle mass and function), frailty and reduced quality of life. Lead researcher Prof Ailsa Welch, from UEA’s Norwich Medical School said: “As people age, they lose skeletal muscle mass and strength.”People over 50 lose up to one percent of their skeletal muscle mass each year, and this loss is thought to affect more than 50 million people worldwide.”

“It’s a big problem because it can lead to frailty and other poor outcomes such as sarcopenia, physical disability, type-2 diabetes, reduced quality of life, and death.”

“We know that Vitamin C consumption is linked with skeletal muscle mass. It helps defend the cells and tissues that make up the body from potentially harmful free radical substances. Unopposed these free radicals can contribute to the destruction of muscle, thus speeding up age-related decline.”But until now, few studies have investigated the importance of Vitamin C intake for older people. We wanted to find out whether people eating more Vitamin C had more muscle mass than other people.”Dr. Richard Hayhoe, also from UEA’s Norwich Medical School, said: “We studied a large sample of older Norfolk residents and found that people with the highest amounts of vitamin C in their diet or blood had the greatest estimated skeletal muscle mass, compared to those with the lowest amounts. We are very excited by our findings as they suggest that dietary vitamin C is important for muscle health in older men and women and may be useful for preventing age-related muscle loss. This is particularly significant as Vitamin C is readily available in fruits and vegetables, or supplements, so improving intake of this vitamin is relatively straightforward.”We found that nearly 60 percent of men and 50 percent of women participants were not consuming as much Vitamin C as they should, according to the European Food Safety Agency recommendations.”We’re not talking about people needing mega-doses. Eating citrus fruit, such as orange, each day, and having a vegetable side to a meal will be sufficient for most people.”

The research was led by the University of East Anglia, in collaboration with the University of Cambridge and Strange ways Research Laboratory in Cambridge, and developed from a UEA medical student project by Lucy Lewis. Older people who eat plenty of vitamin C – commonly found in citrus fruits, berries, and vegetables – have the best skeletal muscle mass, according to new research.Lead researcher Prof Ailsa Welch, from UEA’s Norwich Medical School said: “As people age, they lose skeletal muscle mass and strength. People over 50 lose up to one percent of their skeletal muscle mass each year, and this loss is thought to affect more than 50 million people worldwide. It’s a big problem because it can lead to frailty and other poor outcomes such as sarcopenia, physical disability, type-2 diabetes, reduced quality of life, and death.”

The research team studied data from more than 13,000 people aged between 42-82 years, who are taking part in the EPIC (European Prospective Investigation into Cancer and Nutrition) Norfolk Study.

They calculated their skeletal muscle mass and analyzed their vitamin C intakes from a seven-day food diary. They also examined the amount of vitamin C in their blood. Dr. Richard Hayhoe, also from UEA’s Norwich Medical School, said: “We studied a large sample of older Norfolk residents and found that people with the highest amounts of vitamin C in their diet or blood had the greatest estimated skeletal muscle mass, compared to those with the lowest amounts. Vitamin C-rich foods were found to help maintain skeletal muscle mass in older adults that could help avoid weak muscles in later life. Vitamin C has physiological relevance to skeletal muscle and may protect it during aging. Researchers at the University of East Anglia (UEA) claimed after doing thorough research to determine cross-sectional associations of dietary and plasma vitamin C with proxy measures of skeletal muscle mass in a large cohort of middle- and older-aged individuals. The findings of the study were published in ‘The Journal Of Nutrition. Dietary intake of each participant was assessed using a 7-d food diary. The participants recorded all food and drink consumed within a 7-d period, including details of portion sizes. The mechanistic roles for vitamin C in skeletal muscle physiology include the synthesis of carnitine and collagen. Collagen is a key structural component of skeletal muscle cells and tendons, and carnitine is essential for the metabolism of long-chain fatty acids during physical activity.”Analysis of dietary data for our cohort showed that for both men and women the greatest contributors to vitamin C intake were fruits, vegetables, potatoes, and fruit juices. Although such foods are typically readily available and easy to prepare and small increases in daily consumption should be achievable, limitations in income, access, and availability exist in at-risk populations,” added Prof Welch.

Hopefully, after learning all the benefits of taking Vitamin C on a regular basis, you will decide to take a Vitamin C supplement and start taking it now. Regardless of whether you are looking to pack on size, get stronger, lose weight, compete, or just stay in great shape, C is one of those vitamins that will go a long way of helping you reach all of your fitness goals.

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World Human Spirit Day Thoughts

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World Human Spirit Day Thought

February 17 is observed as the World Human Spirit Day to encourage mindfulness through meditation. World Human Spirit Day was started in 2003 by Michael Levy to serve as the day to promote a human spirit that lives a creative, peaceful, and loving life.

Here are a few quotes for the World Human Spirit Day

The human spirit was the strongest medicine on earth. And sometimes all it needed was a little encouragement to pull off a miracle.

The human body has limitations; the human spirit is boundless. – Dean Karnazes

Man never made any material as resilient as human spirit. – Bernard Williams

The human spirit is stronger than anything that can happen to it. – C C Scott

Difficulties are meant to rouse not discourage. The human spirit is to grow strong by conflict. – William Ellery Channing

Freedom is one of the deepest and noblest aspirations of the human spirit. – Ronald Reagan

You have to, in some ways, trust in the human spirit and in human ingenuity. – Ariel Garten

Don’t ever forget that you’re a citizen of this world, and there are things you can do to lift the human spirit, things are easy, things are free, things that you can do every day. Civility, respect, kindness, character. – Aaron sorkin

Ways to develop Human Spirit

  1. Meditation
  2. Talk to yourself
  3. Prayer
  4. Fill with positive words

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Vitamin B3 Protects Skin Cells From The Effects Of UV Exposure, New Research Finds

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We all know just how important eating our vitamins are. Vitamins are essential nutrients that nourish our body and keep vital organs functioning smoothly. While some help with immunity, others regulate the skin and hair.

And turns out a few of them can even keep you safe from cancer. In fact, a recent study found that increasing the consumption of vitamin B3 can protect the skin from the ill-effects of UV rays, potentially reducing the incidence of non-melanoma skin cancers.

Researchers in Italy isolated cells (human primary keratinocytes) from the skin of patients with non-melanoma skin cancers. These cells were treated with three different concentrations of nicotinamide (NAM), a form of vitamin B3, for 18, 24, and 48 hours and then exposed to UVB rays.

Vitamin B3 can work wonders when it comes to protecting the skin:

Results show that pre-treatment with 25mM of NAM 24 hours before UV irradiation protected the skin cells from the effects of UV-induced oxidative stress, including DNA damage. Furthermore, it decreased antioxidant expression and blocked local inflammation by showing decreased nitric oxide release and reactive oxygen species (ROS) production and reduced iNOS protein expression.

Lara Camillo, a research student from the dermatological unit of AOU universitaria Maggiore della Carita, Novara, Italy says: “Our study indicates that increasing the consumption of vitamin B3, which is readily available in the daily diet, will protect the skin from some of the effects of UV exposure, potentially reducing the incidence of non-melanoma skin cancers. However, the protective effect of vitamin B3 is short-acting, so it should be consumed no later than 24 to 48 hours before sun exposure.”

Research presented today at EADV’s 29th Congress, EADV Virtual, shows hope that a form of vitamin B3 could protect skin cells from the effects of ultraviolet (UV) exposure: the main risk factor for non-melanoma skin cancers.

Researchers in Italy isolated cells (human primary keratinocytes) from the skin of patients with non-melanoma skin cancers. These cells were treated with three different concentrations of nicotinamide (NAM), a form of vitamin B3, for 18, 24, and 48 hours and then exposed to UVB.

Results show that pre-treatment with 25μM of NAM 24 hours before UV irradiation protected the skin cells from the effects of UV-induced oxidative stress, including DNA damage. NAM enhanced DNA repair, demonstrated by decreased expression of the DNA repair enzyme OGG1. Furthermore, it decreased antioxidant expression and blocked local inflammation by showing decreased nitric oxide (NO) release and reactive oxygen species (ROS) production, and reduced iNOS protein expression.

Lara Camillo, a research student from the Dermatological Unit of AOU Maggiore della Carità, Novara, Italy says: “Our study indicates that increasing the consumption of vitamin B3, which is readily available in the daily diet, will protect the skin from some of the effects of UV exposure, potentially reducing the incidence of non-melanoma skin cancers. However, the protective effect of vitamin B3 is short-acting, so it should be consumed no later than 24 to 48 hours before sun exposure.”

Non-melanoma skin cancers are the most common malignancies in the Caucasian population and incidence is increasing worldwide. The main risk factor is UV radiation exposure, which damages the DNA, increases ROS production, activates local inflammation, and depletes cellular energy, leading to genomic instability and cell death.

About skin cancer:

There are two main types of skin cancer: non-melanoma skin cancer (which includes basal cell skin cancer, squamous cell skin cancer and other rare types) and melanoma skin cancer. Basal and squamous cell cancers are most often found in areas exposed to the sun, such as the head, neck, and arms, but they also can occur elsewhere (2). They are very common but are usually very treatable (2). Melanoma is a type of skin cancer that develops when melanocytes (the cells that give the skin its tan or brown colour) start to grow out of control (3). Melanoma is much less common than some other types of skin cancers but is more dangerous because it’s much more likely to spread to other parts of the body if not caught and treated early (3). Non-melanoma skin cancer is the 5th most commonly occurring cancer in men and women, with over 1 million diagnoses worldwide in 2018.4 Melanoma of the skin is the 19th most commonly occurring cancer in men and women, with nearly 300,000 new cases in 2018.

About EADV:

Founded in 1987, EADV is the leading community to further the knowledge of health professionals and advocates in the field of dermatology and venereology. It is a non-profit organization with over 7,000 members, across 113 different countries in the world, providing a valuable service for every type of dermato-venereologists professional. The EADV is committed to improving the quality of patient care, continuing medical education for all dermato-venereologists within Europe and beyond, and advocacy on behalf of the specialty and patients.

About EADV Virtual:

This year’s Congress is a first in EADV’s history. EADV Virtual – New Frontiers in Dermatology and Venereology provides an exceptional opportunity for colleagues from around the world to explore the latest developments in science and patient care that are at the heart of the academy’s mission. The user experience is immersive and simple to follow.

 

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Passion fruit: what are the health and medicinal benefits of passion fruit? What do you know about passion fruit?

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Modern lifestyle diseases, such as obesity and metabolic syndrome (MS), may lead to many complications, including hypertension, diabetes, hyperlipidemia and cardiovascular disease. They also accelerate the aging processes. Appropriate dietary interventions may help to regulate glucose and energy metabolism, and thus improve the outcome for affected individuals.

Among the interventions are caloric restriction, which helps reduce insulin resistance by preventing sustained hyperglycemia. This often requires long-term control of dietary choice and portion size, which is difficult to maintain for a majority of overweight subjects. For this reason, functional foods, such as passion fruit are being studied for their potential contribution to reducing weight and insulin resistance.

Metabolic Benefits

One compound in passion fruit, which has garnered plenty of interest is piceatannol, an analog of resveratrol. The latter is a polyphenol, which has been shown to lower glucose levels, and to increase stamina, in several rodent studies.

A clinical study on resveratrol in humans with excessively high body mass index (BMI) confirmed these results, as well as its ability to produce a reduction in blood pressure and higher mitochondrial respiration in muscle tissue, as well as the activation of several muscle kinases. Piceatannol shares many of these benefits, improving metabolic parameters and glucose breakdown, reducing vascular tone, increasing eNOS levels (which is vaso-protective), promoting collagen synthesis, and reducing ultraviolet damage to the skin. In fact, its activity is higher than that of resveratrol.

One study showed that insulin levels in serum were significantly reduced in the fasting state in overweight men with piceatannol supplementation, as well as a fall in the blood pressure and the heart rate. This was not seen in women or in men with a normal BMI. Another study in mice showed inhibition of postprandial rises in blood glucose levels as well, which points to the potential for anti-diabetic activity with piceatannol supplements. Further studies are needed to understand the variation in effect with body composition and gender, as well as to perform more sensitive and long-term evaluations of the changes in glucose and insulin parameters.

Cardiovascular Benefits

The cardiovascular effects of piceatannol seem to be mediated by the antioxidant and anti-inflammatory effects of the polyphenol. It is known that failure of vasorelaxation, which is mediated by eNOS activity, is a characteristic of endothelial dysfunction. This would lead eventually to atherosclerosis via lipid oxidation and inflammation of blood vessels. It also activates dimethylarginine dimethylaminohydrolase, and thus inhibits the natural deactivation of eNOS. Again, it increases eNOS stability, thus prolonging its half-life. It has other mechanisms of vascular anti-inflammatory action as well. Piceatannol thus has profound cardioprotective effects, and a central mechanism of action cannot be ruled out as well. In addition, it may help to stabilize cardiac myocytes.

Each 100g serving of passion fruit supplies about 30g potassium, or a quarter of the daily requirement. This is one of the best things to do to reduce cardiovascular risk. Potassium is a vasodilator, and it is necessary for the operation of the vital ion channels in the cell membranes.

Antioxidant Benefits

Passion fruit also contains many other antioxidants, such as C-glycosyl flavonoids, chlorogenic acid, isovitexin, caffeic acid, quercetin, rutin, and luteolin. These also play a role in glycemic and lipid control, but the exact effects and doses have to be elucidated through further study. A single serving can contain about 30g of vitamin C, and significant amounts of carotene and cryptoxanthin, all of which are powerful antioxidant molecules lowering the risk of age-related degeneration, cancers, and cardiovascular disease. Vitamin C also stimulates collagen synthesis and improves epithelial health, as well as being an immunomodulator to boost innate immunity.

Dietary Fiber

Passion fruits also contain large amounts of dietary fiber (98% of the daily recommended intake), which helps improve intestinal health, reduces the pH and ammonia levels in the colon and thus encourages healthy intestinal microbiota, and relieves constipation and flatulence. Again, fiber reduces appetite and this again leads to lower insulin levels and reversal of the metabolic syndrome. It also results in lower levels of cholesterol in the blood. The rind of the fruit is also rich in soluble fiber, which has independent anti-diabetic and anti-dyslipidemic effects. Fiber also lowers the risk of colorectal cancer. Piceatannol also counteracts colonic irritation leading to intestinal inflammation.

Eye Health

The large amounts of vitamin A in passion fruit can safeguard eye health against age-related macular degeneration, prevent cataracts, and lower the rate of skin aging and wrinkling.

Anemia

Passion fruit also contains appreciable amounts of copper, iron, magnesium and phosphorus, contributing to bone health and to normal RBC counts, which helps to counter anemia.

Anxiolytic Benefits

Some rodent studies found a marked anxiolytic and sedative effect upon supplementing the diet with passion fruit, due to the alkaloid harman. This can also help to relieve insomnia.

Anti-Tumor Benefits

Anticancer effects include apoptotic actions upon human cancer cell lines, as well as inhibition of migration and epithelial anchoring of metastatic cells in breast and prostate cancer. Piceatannol also inhibits HDL uptake by neurons to which ecto-F1-ATPase autoantibodies are bound. It may thus may slow the development and progression of Alzheimer’s disease. It may also inhibit antigen-induced WBC degranulation and thus prevent allergic reactions.

Conclusion

Passion fruit is not just a delicious tropical addition to the menu, but a powerhouse of several potential health benefits and should become a part of a varied and rich diet whenever available in season.

 

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